Act One

  • Overture − Orchestra
  • St. Bridget − Agnes, Young Patrick
  • It's Today − Mame, Ensemble
  • It's Today (Reprise) - Mame, Young Patrick
  • Open a New Window − Mame, Ensemble
  • The Moon Song (The Man in the Moon) − Vera, Mame, Girls
  • My Best Girl − Young Patrick, Mame
  • We Need a Little Christmas − Mame, Young Patrick, Agnes, Ito, Beauregard
  • The Fox Hunt − Uncle Jeff, Young Patrick, Cousin Fan, Mother Burnside, Cousins
  • Mame − Beauregard Jackson Picket Burnside, Ensemble
  • Finale Act I ("My Best Girl" and "Mame") − Young Patrick and All

Act Two

  • Opening Act Two (The Letter) − Young Patrick, Older Patrick
  • My Best Girl (Reprise) − Older Patrick
  • Bosom Buddies − Mame, Vera
  • Gooch's Song − Agnes
  • That's How Young I Feel − Mame, Ensemble
  • If He Walked Into My Life − Mame
  • It's Today (Reprise) − Mame, Ensemble
  • My Best Girl (Reprise) − Older Patrick
  • Finale Act II ("Open A New Window") − Company

A song with an asterisk (*) before the title indicates a dance number.