Set in the 1950s, Leading Ladies focuses on two English Shakespearean actors, Jack and Leo, who find their careers in a rut. They are currently performing "Scenes from Shakespeare" on the Moose Lodge circuit in the Amish country of Pennsylvania. When they hear that an old lady in York, PA is about to die and leave her fortune to her two long lost English nephews, however the actors resolve to pass themselves off as her beloved relatives and get the cash. Hilarity ensues when it turns out the relatives are actually nieces and not nephews. Things get even more complicated when Leo falls madly in love with the old lady's vivacious niece, Meg, who's engaged to the local minister.
Leading Ladies guide sections